6 Natural Lectin Blockers (and How to Get More of Them)

by | Jan 18, 2023

Stop Lectins Before They Stop You

Lectins are not your friends, and you want to block them from getting into your body. If you’re reading this you’re probably well aware that they can wreak havoc on your immune system and have been implicated in a variety of diseases–as well as weight gain. Wouldn’t it be nice if you could block them from entering your system, altogether?

First Line of Defense: Avoidance

The best way to avoid the harmful effects of lectins is to not consume them in the first place. But unless you plan to starve yourself, realistically it’s going to be hard to do so 100% of the time. 

So where does that leave us? Do what you can to avoid foods with lectins, and add things to your diet that block lectins as much as possible, in order to mitigate their harmful effects. If you like to cook, don’t miss my compilation of Dr. Gundry’s Plant Paradox recipes, as many of them can help you do both.

Nature’s Natural Lectin Blockers

There are plenty of naturally occurring lectin-blocking compounds in common foods, which means you can integrate them into your diet with relative ease.

The top six natural lectin-blocking foods that you should consume more of are okra, crustaceans, bladderwrack (seaweed), pigs feet, cranberries and kiwifruit.

They all come with unique lectin-lectin blocking properties. Read on to learn how they work their magic.

1. Okra: Polysaccharide Powerhouse 

okra lectin blocker

Okra is rich in raw polysaccharide (RPS), a potent compound that has been shown to bind to lectins, effectively blocking their ability to cause cause harm (1), With high concentrations of polyphenols and other antioxidants, okra has been shown to have powerful medicinal properties, including protecting against fatigue (2).

Where to get it: Okra is available fresh at most grocery stores. Get started by whipping up some of Dr. Gundry’s Lectin-Blocking Okra Chips

2. Crustaceans: Get a Glut of Glucosamine 

crustaceans lectin blocker

Crustacean skins and shells contain glucosamine, a compound that binds to lectins in wheat (3). Since wheat lectins are known to cause joint problems (4), this lectin blocker is also a common ingredient in supplements for joint health.

Where to get it: The shells of shrimp, crabs, lobster and crawfish contain lots of glucosamine. In fact, glucosamine supplements are often made from them. So next time you make seafood, don’t toss these goodies away. Instead, grind them up and add a little to your dishes. Shrimp shells can also be eaten as is–in fact, many cultures do just that.

3. Bladderwrack: Give Lectins the Slip 

bladderwrack lectin blocker

This simple seaweed has been shown to be a potent lectin blocker (5), and studies also suggest it has antifungal properties against Candida yeasts (6). The benefits of Bladderwrack go further: With high levels of mucilage, beta-carotene, iodine, potassium, zeaxanthin, and other organic compounds, this sea creature is potent! It’s been shown to help with digestive issues, weight loss, thyroid conditions, inflammation and more.

Where to get it: Bladderwrack grows on the northern Atlantic and Pacific coasts of the US as well as parts of Europe. So next time you’re at the beach, bend over and grab some Bladderwrack, and head to the kitchen. If you’re landlocked and can’t find it fresh, it’s widely available in supplement form.

4. Pigs Feet: Gross But Good For You

pigs feet glucosamine

Glucosamine is also naturally occurring in cartilaginous offal (“Offal” is a slightly less unappetizing word for organ meets, animal entrails, etc.). So next time you make stew don’t forget to toss some pigs feet into the broth, or even serve them on their own. They’re great not just for blocking lectins, but for your gut in general. Bone broth also has glucosamine.

Where to get it: Your local butcher shop.

5. Cranberries: Destroy Lectins with D-Mannose 

d-mannose cranberries lectins

Cranberries, oranges, peaches and blueberries contain D-Mannose, a powerful natural compound that binds to lectins, including those in legumes (7). Research suggests that D-Mannose can also protect against infections (8). This compound also has broad benefits that go beyond blocking lectins: it can help help maintain urinary tract and gastrointestinal health.

Where to get it: D-Mannose is easy to come by. It’s plentiful in many of the fruits you eat every day.

6. Kiwifruit: Boost Mucin, Block Lectins 

lectin blocker kiwis

Kiwifruit increases your body’s production of mucin, which helps to form a slippery protective barrier inside your digestive tract (9). The sialic acid in mucin binds to multiple sources of foods containing lectins, blocking them from permeating the wall of your gut. This includes lectins found in wheat (10).

Where to get it: mucin doesn’t occur naturally in foods, per se. Rather, it’s produced by your body, depending on what you eat. Slippery fruits, especially kiwis, have been shown in studies to increase mucin secretion (11).

Lectin Shield: Lectin Blocker In a Bottle

While it’s generally preferred to get nutrients from whole foods instead of supplements, sometimes that’s just not realistic. If you know you’re heading into a lectin-laden meal, or you want to be more aggressive and block lectins around the clock, you may want to consider taking a lectin blocker supplement.

Dr. Gundry’s best-selling Lectin Shield is probably the best choice. It contains most of the ingredients listed in this article, and more.

Lectin Shield Reviews

Based on the hundreds of five-star user reviews people feel great while taking Lectin Shield (it’s reported to help with weight loss, digestion, energy and more). If it doesn’t work for you it’s backed by Dr. Gundry’s famous 90 day money-back guarantee, even if the bottle is empty.

Be sure to buy it through Welless Ambassadors like me because we always get the best prices (typically 30-50% off list). Use this link and the discount will be added automatically.

If you want more information before you buy, you can read my full review of Lectin Shield   

Best Anti-Lectin Supplement: Lectin Resolve, Lectin Lock and Lectin Defense vs. Lectin Shield

What’s the best anti-lectin supplement? I’ve had people writing in and asking me what I think of other lectin blocker supplements, including Lectin Resolve, Lectin Lock and Lectin Defense. You might be able to find them at Walmart or GNC (but you should avoid them).

How do they measure up to Lectin Shield? The answer is simple: they don’t. They’re all knock-offs of Dr. Gundry’s original formula. It’s cheaper, of course, but the manufacturer is not reputable like GundryMD and that usually means poor quality. For example, Lectin Resolve, which is made by unknown company Performance Improvement Labs, does not even list what the ingredients are. That tells you all you need to know!

Do not entrust your health to shady supplement companies: Go with the original to avoid scams. Plus, when you get Lectin Shield on the Wellness Ambassadors website the prices are about the same anyway.


1. Cederberg BM, Gray GR. N-Acetyl-D-glucosamine binding lectins. A model system for the study of binding specificity. Anal Biochem. Oct 15, 1979; 99 (1): 221-30. DOI:10.1016/0003-2697(79)90067-8.

2. Freed DLJ. Do dietary lectins cause disease? BMJ. Apr 17, 1999; 318 (7190): 1023-4. DOI: 10.1136/bmj.318.7190.1023.

3. Houser J, Komarek J, Kostlanova N, et. al. A soluble fucose-specific lectin from Aspergillus fumigatus conidia–structure, specificity and possible role in fungal pathogenicity. PLoS One. Dec 10, 2013; 8 (12): e83077. DOI: 10.1371/journal.pone.0083077.

4. Criado MT, Ferreiros CM. Selective interaction of a Fucus vesiculosus lectin-like mucopolysaccharide with several Candida species. Ann Microbiol (Paris). Mar-Apr 1983; 134A (2): 149-54. DOI: 10.1016/S0769-2609(83)80074-X.

5. Hankins CN, Kindinger JI, Shannon LM. Legume Lectins: I. Immunological Cross-Reactions between the Enzymic Lectin from Mung Beans and other Well Characterized Legume Lectins. Plant Physiol. Jul 1979; 64 (1): 104-7. DOI: 10.1104/pp.64.1.104.

6. Ofek I, Beachey EH. Mannose binding and epithelial cell adherence of Escherichia coli. Infect Immun. Oct 1978; 22 (1): 247-54. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC422142/. Accessed July 29, 2016.

7. Wu AM, Jiang YJ, Hwang PY, Shen FS. Characterization of the okra mucilage by interaction with Gal, GalNAc and GlcNAc specific lectins. Biochim Biophys Acta. Feb 23, 1995; 1243 (2): 157-60. DOI: 10.1016/0304-4165(94)00130-P.

8. Xia F, Zhong Y, Li M, et. al. Antioxidant and Anti-Fatigue Constituents of Okra. Nutrients. Oct 26, 2015; 7 (10): 8846-58. DOI: 10.3390/nu7105435.

9. McGuckin MA, Lindén SK, Sutton P, Florin TH. Mucin dynamics and enteric pathogens. Nat Rev Microbiol. Apr 2011; 9 (4): 265-78. DOI: 10.1038/nrmicro2538.

10. Lehmann F, Tiralongo E, Tiralongo J. Sialic acid-specific lectins: occurrence, specificity and function. Cell Mol Life Sci. Jun 2006; 63 (12): 1331-54. DOI: 10.1007/s00018-005-5589-y.

11. Yuan Kun Lee, Kay Yi Low, Kiwifruit (Actinidia deliciosa) changes intestinal microbial profile Microb Ecol Health Dis. 2012; 23: 10.3402/mehd.v23i0.18572.PMCID: PMC3747767


What’s the best lectin blocker supplement?

Dr. Gundry‘s Lectin Shield, the original anti-lectin supplement, is the most popular lectin blocker on the market today. Everything else out there, including Lectin Resolve, Lectin Defense, Lectin Guard and Lectin Defense, is a copycat. Lectin Shield is a premium product that does not come cheap, but with hundreds of five star reviews it’s worth it. The good news is that you can use the special link above to get 40% off. It’s backed by Dr. Gundry’s legendary 90 day money-back guarantee, so you’ve got nothing to lose by trying it!

How can I save 40% on Lectin Shield?

The special links above in this article will take you to the Gundry Wellness Ambassadors website, where all Gundry MD products are available for up to 40% off. Please note that you cannot find the Wellness Ambassadors website by searching on Google; its available exclusively through official ambassadors like Human Food Bar, when you click on the above links. Don’t buy on Amazon or the main Gundry MD website, as you will pay full retail. Everything on the Wellness Ambassadors website is backed by Dr. Gundry’s legendary 90 day money-back guarantee.

Is it really possible to block lectins?

Lectins are everywhere. You should do your best to avoid foods that contain them, but realistically that’s not always possible. That’s where lectin blockers come in. Integrate the recommended foods into your diet as much as possible to protect yourself, and consider taking a lectin blocker supplement, especially if you know you are going to be eating foods that contain lectins.

What are the best natural lectin blockers?

We have identified six foods that naturally contain lectin blocking compounds: Okra, because it has polysaccharides; crustaceans, because they are rich in glucosamine; bladderwrack, which also has strong antifungal properties against candida; pigs feet, which contain glucosamine; cranberries, which destroyed lectins with d-mannose; kiwi fruit, which blocks lectins by boosting mucin production.

Remy is the founder of Human Food Bar. A health and wellness enthusiast based in Berkeley, California with a deep interest in dietary nutrition, he’s well versed in the Plant Paradox, Keto, Paleo and Vegan diets. He has a borderline obsession with nutrition bars that eventually gave birth to the Human Food Bar. In his free time he likes to blog, cook, mixologize, garden and mountain bike.
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Registered Dietitian Nutritionist, Nutritional Synergy
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Kathy is a Registered Dietitian Nutritionist with a Master of Science degree from Michigan State University in Human Nutrition. She’s been a Registered Dietitian for 32 years serving in all capacities of my profession from clinical nutrition to public health and education. She’s passionate about helping people change their lives for the better using medical nutrition therapy and in the art and practice of writing about all aspects of functional and integrative nutrition.
Remy is the founder of Human Food Bar. A health and wellness enthusiast based in Berkeley, California with a deep interest in dietary nutrition, he’s well versed in the Plant Paradox, Keto, Paleo and Vegan diets. He has a borderline obsession with nutrition bars that eventually gave birth to the Human Food Bar. In his free time he likes to blog, cook, mixologize, garden and mountain bike.

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